2015 SPRING - Disrupting IT for Biopharma R&D

DATE, LOCATION & HOST

The spring 2015 PRISME Forum Technical Meeting was held Thursday, May 21, 2015 and was hosted by F. Hoffmann-La Roche at its campus in Kaiseraugst, Switzerland.

The meeting was preceded by a networking reception the evening of Wednesday, the 20th of May.

PRISME Forum Technical Meeting Chair:
Martin Erkens, F. Hoffmann-La Roche

PRISME Forum Chair:
Olivier Gien, Sanofi

SPRING 2015 TECH MEETING

Thursday, May 21, 2015

Meeting hosted by F. Hoffmann-La Roche

Disrupting IT for Biopharma R&D

BACKGROUND	Pharma R&D is evolving rapidly. Not least, it is seeking to meet the challenges of loss of drug exclusivity and the industry-wide pressure to deliver innovative medicines to serve unmet medical need at lower cost, and more quickly. Furthermore, this must be achieved in compliance within an increasingly demanding and somewhat uncertain regulatory environment. Imaging technologies, genomics/genetics, the digitization of medical information, the rapid development of sensor technologies and patient-centered approaches are all changing the data inputs into bio-pharma R&D. These different modalities add to an already data-intensive, and data-driven, drug discovery and development process. Bio-pharma R&D IT groups are currently striving to harness the power of this myriad of new developments. The bringing together of these new technologies can - and should - disrupt traditional R&D processes. Such disruptive R&D IT developments can re-engineer existing infrastructure, streamline business processes, speed up cycle times and importantly advance science. Such disruptive innovation can empower a patient-centred, more efficient approach to bio-pharma R&D and help bring relevant and important new medicines to market.
FOCUS	The agenda for this PRISME Forum Spring 2015 Technical Meeting will focus on case studies in the use of disruptive technologies and the value that they are currently demonstrating or are predicted to have. PRISME Forum members are invited to consider – and indeed supplement - the following questions: 1. How can R&D IT leverage disruptive approaches to improve R&D’s understanding of science and enhance its value to patients? 2. What will the future bio-pharma R&D information ecosystem look like? 3. How can we embrace these technologies quickly while avoiding costly mistakes? 4. How are patients and their patient-care organisations, and physicians along with health-care providers changing the way they collect and leverage their data and what opportunities exist for Pharma companies to be partners in this disruption? The PRISME Forum Technical Meeting Advisory Committee will be looking for qualified speakers to address relevant topics including: - Use cases demonstrating how disruptive technologies have enhanced bio-pharma R&D - The “internet of things” changing capability to monitor processes and systems within R&D labs. - Mobile sensors and social medial changing our ability to monitor patients, understand disease and responses to drugs – including regulatory impacts (with a focus on the European regulators). - Disruptive technologies- empowering new services – thereby lowering the barrier to entry to biopharma R&D - The consumerization of IT challenging R&D IT teams to deliver great user experiences across multiple platforms including the traditional enterprise systems - Experiences and examples from technology suppliers of disruptive technology-driven innovation that either directly - or by analogy - will provide opportunities for R&D and R&D IT.
MEETING OUTCOMES	PRISME Forum members will be able to identify and define disruptive phenomena (including technologies, services and business models) that can impact R&D in their parent companies and find opportunities to partner to deliver pre-competitive capabilities that increase the effectiveness of R&D.
CHAIRS and TECHNICAL MEETING ADVISORY COMMITTEE	The PRISME Forum has invited Martin Erkens (Roche) to lead the Technical Meeting Advisory Committee on which the following PRISME Forum members have all very kindly agreed to serve: Ingrid Akerblom (Amgen), Jim McGurk (Daiichi-Sankyo), Martin Leach (Biogen Idec), Preben Klavsen (Lundbeck), John Apathy (Celgene).
STRUCTURE	Wednesday, May 20, 2015: The PRISME Forum arranges an informal, networking dinner the evening before its Technical Meetings; Thursday, May 21, 2015: Technical Meeting. Note: There will be an awards ceremony and an informal networking reception at the end of the Technical Meeting.

All sessions will be held at F. Hoffmann-La Roche campus in Kaiseraugst.

TIME	SESSION	SPEAKER/CHAIR
Wednesday, May 20, 2015
19:00	Joint PRISME Forum Business Group + Tech Group Reception
Thursday, May 21, 2015
7:30	Shuttle transfer between hotel and meeting venue
8:00	Check-in and poster installation
8:20	Welcome Notes	Olivier Gien, Chair, PRISME Forum; Global Head of R&D Health Information Technology, Sanofi
8:25	Introduction	Martin Erkens, Chair, PRISME Forum Tech Meeting; Global Area Head - Research Informatics, Hoffmann-La Roche AG
8:30	SESSION 1: PERSPECTIVES	CHAIR: Martin Erkens, Chair, PRISME Forum Tech Meeting; Global Area Head - Research Informatics, Hoffmann-La Roche AG
8:30	Lecture 1: Accelerating Disruption in Pharma R&D Technology and the Influence of Venture Capital	Matthew Rich, Partner, PwC James Golden, Senior Managing Director, PwC
9:00	Lecture 2: 3D Printed MicroRobots for NanoMedicine	Bradley Nelson, Professor, Robotics and Intelligent Systems, ETH Zürich
9:30	Lecture 3: Human Brain Project	Richard Frackowiak, Professor, EPFL
10:00	Coffee Break
10:30	Panel Discussion – “From Search to Cognition: Are We There Yet?”	MODERATOR: John Apathy, VP, R&D Informatics, Celgene Alexandre Bilger, CEO, Sinequa Stefan Geißler, Managing Director, TEMIS Deutschland GmbH Scott Spangler, Principal Data Scientist, IBM Research,
11:30	SESSION 2: POSTERS and DEMONSTRATIONS	CHAIR: James McGurk, Senior Director, Global Head, Data Architecture, R&D Informatics, Daiichi-Sankyo
11:30	Introduction and Logistics
11:40	Poster Session (Four 15 min rotations)
	P1: Open Innovation at Bayer	Jamie Showrank, Global IT Innovation Manager, Bayer
	P2: Remote Digital Biomarker Monitoring - Bringing a Smartphone-based Diagnostic Test for Parkinson’s Disease Progression into an Interventional Trial	Christian Gossens, Global Head Early Development Workflows, Research & Early Development, F. Hoffmann-La Roche
	P3: Wearable Technology and Associated Data Collection Apps in Clinical Trials	Mike Bartlett, Enterprise Architect, Lundbeck
	P4: Extending from Personal Wellness – Considerations for Using Wearables in Clinical Trials	Marie McCarty, Director of Product Innovation, ICON PLC
	P5: VOS: Virtual On Site Monitoring	Luca Emili, Founder and CEO, Promeditec
	P6: Big Data Search & Analytics in Complex Pharma - Data Extracting Relevant and Valuable Information for Pharma Users from Diverse Data Sets	Alexandre Bilger, CEO, Sinequa Luc Manigot, VP, Global Operations, Sinequa
	P7: Will Our Lives Be Improved by Smartphones and Sensors?	Achim Heger, Researcher and Community Organizer, Quantified Self Zürich
12:40	Lunch
13:45	SESSION 2b: POSTERS and DEMONSTRATIONS (cont.)	CHAIR: James McGurk, Senior Director, Global Head, Data Architecture, R&D Informatics, Daiichi-Sankyo
	Poster Session (Remaining three 15 min rotations)
14:30	SESSION 3: KEYNOTE PRESENTATION	CHAIR: Martin Erkens, Head, pRED Informatics, F. Hoffmann-La Roche
	The Next Generation of Games for Health	Phaedra Boinodiris, Global Lead Serious Games and Gamification, IBM
15:00	Coffee Break
15:30	Data Revolutions, AI and Health	Franz Och, Chief Data Scientist, Human Longevity Inc.
16:00	SESSION 4: BRINGING IT ALL TOGETHER	CHAIR: Martin LeachVP, R&D IT, Biogen Idec
	Round Table Discussions (with note takers) Chaired by Technical Meeting Advisory Committee Members
17:00	Read-out of Round Table Discussions
17:30	AWARDS	Martin Erkens, ChairPRISME Forum Tech Meeting, Global Area Head - Research Informatics, Hoffmann-La Roche AG